Hybrids/Conjugates/Chimera Drugs-Antimicrobial Hybrids: Antibiotics, Antifungals, Antituberculars, Antimalarials

Research output: Contribution to journalReview articlepeer-review

Abstract

Antimicrobial hybrids are compounds that can inhibit, stop the growth of, or kill microorganisms, including bacteria, fungi, and parasites. Antibiotics, a subset of antimicrobial agents, specifically target bacteria and include well-established classes such as β-lactams, macrolides, quinolones, and oxazolidinones. Other antimicrobial hybrids are designed for treating a wide range of diseases, including fungal infections, leishmaniasis, parasitic diseases (such as trypanosomiasis and malaria), leprosy, and tuberculosis. Some hybrids are designed to treat a variety of diseases. This review highlights studies primarily published between 2000 and 2023, with a few from 2024, underscoring the dynamic and rapidly evolving nature of antimicrobial hybrid research.

Original languageEnglish
JournalCurrent Medicinal Chemistry
Early online date4 Aug 2025
DOIs
StateE-pub ahead of print - 4 Aug 2025

Bibliographical note

Publisher Copyright:
Bentham Science Publishers

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Hybrids
  • antibiotic
  • antimicrobial
  • fungal infections
  • leishmaniasis
  • leprosy
  • malaria
  • parasitic infections
  • trypanosomiasis

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