Holographic photo-stimulation for dynamic control of neuronal population activity

Suhail Matar, Lior Golan, Nairouz Farah, Inna Reutsky, Shy Shoham

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Spatiotemporal patterns of activity carried across large populations of neurons are the fundamental representation of information within the nervous system. Patterned optical photo-stimulation of neural populations provides a general strategy for controlling such spatial-temporal patterns, but previous realizations of this technology did not allow high-rate, parallel, light-efficient control of large neural populations. To address this challenge, we have been developing a new generation of holographic pattern photo-stimulation systems that use phase-only spatial light modulators (SLM) to create computer-controlled light patterns in two and three dimensions. SLMs use phase modulation and light diffraction to provide a light-efficient method for flexibly creating desired light patterns which can be switched in our systems in millisecond timescales. Holographic photo-stimulation provides a powerful strategy for dynamic patterned photo-stimulation of neural populations and could be used in research and neuroprosthetic interfaces.

Original languageEnglish
Title of host publication2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
Pages84-87
Number of pages4
DOIs
StatePublished - 2009
Externally publishedYes
Event2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09 - Antalya, Turkey
Duration: 29 Apr 20092 May 2009

Publication series

Name2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09

Conference

Conference2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09
Country/TerritoryTurkey
CityAntalya
Period29/04/092/05/09

Keywords

  • ChRII
  • High-rate photo-stimulation
  • Holography
  • Optical control
  • SLM
  • Two-photon

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