High-yielding and rapid carbon-carbon bond formation from alcohols: Allylation by means of TiCl4

Alfred Hassner, Chennakesava Reddy Bandi

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

TiCl4 efficiently promotes high yield (80-99%) replacement of OH in tertiary, benzylic, and allylic alcohols, and even nonactivated secondary alcohols, by an allyl group. The reaction usually proceeds within minutes at room temperature.

Original languageEnglish
Article numberST-2013-B0058-L
Pages (from-to)1275-1279
Number of pages5
JournalSynlett
Volume24
Issue number10
DOIs
StatePublished - 2013

Keywords

  • C-C bonds
  • Lewis acid
  • TiCl
  • alcohols
  • allylation
  • allyltrimethylsilane

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