High resolution CT assessment of the pediatric airways: Structure and function

Sandra S. Kramer, Eric A. Hoffman, Israel Amirav

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations


The airway has always been a central focus for respiratory pathology in infants and children. Imaging of the larynx, trachea and the central bronchi can be readily accomplished by radiographic or conventional CT techniques. Newer high resolution CT (HRCT) techniques have extended our view of the bronchi peripherally to the limits of scanner resolution, ie. to bronchial generations 7-9, and rapid volumetric CT data acquisitions have made it possible to follow the same lung anatomic level through the rapidly occurring changes in a series of experimental protocols. These techniques together with a custom designed computer software program for image display and analysis have enabled us to objectively study changes in airway caliber and lung density which occurred in an animal model of airway reactivity and thereby relate structure with function in the airways.

Original languageEnglish
Pages (from-to)320-329
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 1 May 1994
Externally publishedYes
EventMedical Imaging 1994: Physiology and Function from Multidimensional Images - Newport Beach, United States
Duration: 13 Feb 199418 Feb 1994

Bibliographical note

Publisher Copyright:
© 1994 SPIE. All rights reserved.


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