High-Intensity Functional Training: Molecular Mechanisms and Benefits

Tavor Ben-Zeev, Eitan Okun

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations

Abstract

High-intensity interval training (HIIT) and strength exercise are known to improve health markers, such as cardiovascular health, metabolic health, and cognitive function, as well as to reduce all-cause mortality. High-Intensity Functional Training (HIFT) is a training paradigm derived from both HIIT and strength exercise to elicit greater muscle recruitment than repetitive aerobic exercises, thereby improving both cardiovascular fitness and strength parameters. Herein, we provide a focused review of the known molecular mechanisms that underlie the beneficial effects of HIFT on cardiovascular, metabolic, and cognitive functions.

Original languageEnglish
Pages (from-to)335-338
Number of pages4
JournalNeuroMolecular Medicine
Volume23
Issue number3
Early online date1 Jan 2021
DOIs
StatePublished - Sep 2021

Bibliographical note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.

Funding

This work was funded by the Paul Feder fund for Alzheimer’s disease research. We would like to thank Yael Laure for editing this manuscript. This work was funded by the Paul Feder fund for Alzheimer’s disease research.

Keywords

  • Crossfit®
  • HIFT
  • HIIT
  • Mechanical tension
  • Resistance training
  • mTOR

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