@article{559ba3ed244946edb5589a1b934f6757,
title = "High affinity scFv-hapten pair as a tool for quantum dot labeling and tracking of single proteins in live cells",
abstract = "We describe a general approach to label cell surface proteins using quantum dots (QD) for single-molecule tracking. QDs coated with small-hapten modified peptides are targeted to cell surface fusion proteins containing the corresponding single-chain fragment antibody (scFv). The approach Is illustrated with the small hapten fluorescein (FL) and a high-affinity anti-FL scFv fused to two different proteins in yeast and murlne neuronal cell line N2a.",
author = "Gopal Iyer and Xavier Michalet and Chang, {Yun Pei} and Pinaud, {Fabien F.} and Matyas, {Stephanie E.} and Gregory Payne and Shimon Weiss",
year = "2008",
month = dec,
doi = "10.1021/nl8032284",
language = "אנגלית",
volume = "8",
pages = "4618--4623",
journal = "Nano Letters",
issn = "1530-6984",
publisher = "American Chemical Society",
number = "12",
}