TY - JOUR
T1 - Heteroatom doped blue luminescent carbon dots as a nano-probe for targeted cell labeling and anticancer drug delivery vehicle
AU - Das, Poushali
AU - Ganguly, Sayan
AU - Agarwal, Tarun
AU - Maity, Pritiprasanna
AU - Ghosh, Sabyasachi
AU - Choudhary, Sumita
AU - Gangopadhyay, Subhashis
AU - Maiti, Tapas Kumar
AU - Dhara, Santanu
AU - Banerjee, Susanta
AU - Das, Narayan Chandra
N1 - Publisher Copyright:
© 2019
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Herein, a simple and efficient method to fabricate nitrogen and sulphur doped photoluminescent carbon dots (C-dots) has been judiciously developed for targeting cancer cells. Advancement in newfangled imaging tool for cancer cells is a vital and highly trustworthy strategy for cancer therapy. The fluorescent C-dots prepared from κ-carrageenan and folic acid can serve as an efficient cargo for cancer cell labeling expressing the folate receptor on their surface. The prepared C-dots unveiled good water solubility, excellent photostability, and biocompatibility. The C-dots played the role of nano-vehicle for anticancer drug capecitabine under different pH environments. Also, C-dots were applied as invisible marker and finger print recovery applications. The folate receptor in C-dots led to amazing targetability of cancer cells and which embraces a great promise in biomedical studies.
AB - Herein, a simple and efficient method to fabricate nitrogen and sulphur doped photoluminescent carbon dots (C-dots) has been judiciously developed for targeting cancer cells. Advancement in newfangled imaging tool for cancer cells is a vital and highly trustworthy strategy for cancer therapy. The fluorescent C-dots prepared from κ-carrageenan and folic acid can serve as an efficient cargo for cancer cell labeling expressing the folate receptor on their surface. The prepared C-dots unveiled good water solubility, excellent photostability, and biocompatibility. The C-dots played the role of nano-vehicle for anticancer drug capecitabine under different pH environments. Also, C-dots were applied as invisible marker and finger print recovery applications. The folate receptor in C-dots led to amazing targetability of cancer cells and which embraces a great promise in biomedical studies.
KW - Carbon dots
KW - Cellular imaging
KW - Drug delivery
KW - Invisible marker
KW - Photoluminescence
UR - http://www.scopus.com/inward/record.url?scp=85068828997&partnerID=8YFLogxK
U2 - 10.1016/j.matchemphys.2019.121860
DO - 10.1016/j.matchemphys.2019.121860
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:85068828997
SN - 0254-0584
VL - 237
JO - Materials Chemistry and Physics
JF - Materials Chemistry and Physics
M1 - 121860
ER -