Hepatitis B and C among patients with hidradenitis suppurativa: a population-based study

Jeffrey M. Cohen, Khalaf Kridin, Lourdes M. Perez-Chada, Joseph F. Merola, Arnon D. Cohen

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Hidradenitis suppurativa (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections. Methods: This retrospective cross-sectional study from 1999 to 2015 used the database of Clalit Health Services, the largest managed care organization in Israel, to explore the association between HS and hepatitis B and C. Sociodemographic and clinical information was compared using χ2 tests for sex and socioeconomic status and t-tests for age. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to compare the odds of hepatitis B and C in those with and without HS. Results: In multivariate analysis controlling for sex, age as a continuous variable, Arab ancestry, and history of drug abuse, HS was associated with a 1.87-fold increased odds (95% CI 1.11–3.17, P = 0.019) of hepatitis B (HBV). HS was also associated with HCV in multivariate analysis controlling for sex, age per year, Arab ancestry, alcohol use, and drug use, with a 1.74-fold increased odds (95% CI 1.05–2.89, P = 0.032) of hepatitis C (HCV) among those with HS as compared to controls. Conclusions: This study demonstrated an association between HS and both hepatitis B and hepatitis C.

Original languageEnglish
Pages (from-to)84-88
Number of pages5
JournalInternational Journal of Dermatology
Issue number1
StatePublished - Jan 2022
Externally publishedYes

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