TY - JOUR
T1 - Hepatitis B and C among patients with hidradenitis suppurativa
T2 - a population-based study
AU - Cohen, Jeffrey M.
AU - Kridin, Khalaf
AU - Perez-Chada, Lourdes M.
AU - Merola, Joseph F.
AU - Cohen, Arnon D.
N1 - Publisher Copyright:
© 2021 the International Society of Dermatology
PY - 2022/1
Y1 - 2022/1
N2 - Background: Hidradenitis suppurativa (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections. Methods: This retrospective cross-sectional study from 1999 to 2015 used the database of Clalit Health Services, the largest managed care organization in Israel, to explore the association between HS and hepatitis B and C. Sociodemographic and clinical information was compared using χ2 tests for sex and socioeconomic status and t-tests for age. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to compare the odds of hepatitis B and C in those with and without HS. Results: In multivariate analysis controlling for sex, age as a continuous variable, Arab ancestry, and history of drug abuse, HS was associated with a 1.87-fold increased odds (95% CI 1.11–3.17, P = 0.019) of hepatitis B (HBV). HS was also associated with HCV in multivariate analysis controlling for sex, age per year, Arab ancestry, alcohol use, and drug use, with a 1.74-fold increased odds (95% CI 1.05–2.89, P = 0.032) of hepatitis C (HCV) among those with HS as compared to controls. Conclusions: This study demonstrated an association between HS and both hepatitis B and hepatitis C.
AB - Background: Hidradenitis suppurativa (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections. Methods: This retrospective cross-sectional study from 1999 to 2015 used the database of Clalit Health Services, the largest managed care organization in Israel, to explore the association between HS and hepatitis B and C. Sociodemographic and clinical information was compared using χ2 tests for sex and socioeconomic status and t-tests for age. Logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to compare the odds of hepatitis B and C in those with and without HS. Results: In multivariate analysis controlling for sex, age as a continuous variable, Arab ancestry, and history of drug abuse, HS was associated with a 1.87-fold increased odds (95% CI 1.11–3.17, P = 0.019) of hepatitis B (HBV). HS was also associated with HCV in multivariate analysis controlling for sex, age per year, Arab ancestry, alcohol use, and drug use, with a 1.74-fold increased odds (95% CI 1.05–2.89, P = 0.032) of hepatitis C (HCV) among those with HS as compared to controls. Conclusions: This study demonstrated an association between HS and both hepatitis B and hepatitis C.
UR - http://www.scopus.com/inward/record.url?scp=85105929026&partnerID=8YFLogxK
U2 - 10.1111/ijd.15578
DO - 10.1111/ijd.15578
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C2 - 33998670
AN - SCOPUS:85105929026
SN - 0011-9059
VL - 61
SP - 84
EP - 88
JO - International Journal of Dermatology
JF - International Journal of Dermatology
IS - 1
ER -
