Hemoperfusion with chelating microspheres as a new treatment for severe mercury poisoning

S. Margel; J. Hirsh; I. Harari

Hemoperfusion with chelating microspheres as a new treatment for severe mercury poisoning

S. Margel
, J. Hirsh
, I. Harari

Weizmann Institute of Science

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Monodisperse beads of 1.0 mm diameter composed of polymercaptal microspheres of 0.8 micron average diameter encapsulated with agarose were prepared. The polymercaptal microspheres have high affinity for organic and inorganic mercury compounds and do not bind to alkali and alkaline earth metallic compounds. The agarose-polymercaptal microsphere beads (APMMB) are blood compatible with high porosity. In vitro experiments with a column containing these beads illustrated their efficiency for the removal of mercury from the blood by means of hemoperfusion.

Original language	English
Pages (from-to)	300-305
Number of pages	6
Journal	Archives of Toxicology
Volume	53
Issue number	Suppl. 6
State	Published - 1983
Externally published	Yes

Cite this

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abstract = "Monodisperse beads of 1.0 mm diameter composed of polymercaptal microspheres of 0.8 micron average diameter encapsulated with agarose were prepared. The polymercaptal microspheres have high affinity for organic and inorganic mercury compounds and do not bind to alkali and alkaline earth metallic compounds. The agarose-polymercaptal microsphere beads (APMMB) are blood compatible with high porosity. In vitro experiments with a column containing these beads illustrated their efficiency for the removal of mercury from the blood by means of hemoperfusion.",

author = "S. Margel and J. Hirsh and I. Harari",

year = "1983",

language = "אנגלית",

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N2 - Monodisperse beads of 1.0 mm diameter composed of polymercaptal microspheres of 0.8 micron average diameter encapsulated with agarose were prepared. The polymercaptal microspheres have high affinity for organic and inorganic mercury compounds and do not bind to alkali and alkaline earth metallic compounds. The agarose-polymercaptal microsphere beads (APMMB) are blood compatible with high porosity. In vitro experiments with a column containing these beads illustrated their efficiency for the removal of mercury from the blood by means of hemoperfusion.

AB - Monodisperse beads of 1.0 mm diameter composed of polymercaptal microspheres of 0.8 micron average diameter encapsulated with agarose were prepared. The polymercaptal microspheres have high affinity for organic and inorganic mercury compounds and do not bind to alkali and alkaline earth metallic compounds. The agarose-polymercaptal microsphere beads (APMMB) are blood compatible with high porosity. In vitro experiments with a column containing these beads illustrated their efficiency for the removal of mercury from the blood by means of hemoperfusion.

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IS - Suppl. 6

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Hemoperfusion with chelating microspheres as a new treatment for severe mercury poisoning

Abstract

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