Hemoperfusion for detoxification of mercury. a model:Treatment of severe mercury poisoning by encapsulated chelating spheres, part i.

S. Margel, J. Hirsh

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Polymercaptal microspheres of average size 0.8)u were synthesized. They have very high affinity towards mercury compounds and do not interact with alkali or alkali earth metallic compounds, they can also easily bind mercury compounds which were already bound to albumin or cysteine. Polymercaptal spheres were encapsulated by agarose - a blood compatible polymer. The encapsulated spheres were used successfully by means of plasma perfusion for detoxification of organic and inorganic mercury compounds from poisoned plasma.

Original languageEnglish
Pages (from-to)107-125
Number of pages19
JournalArtificial Cells, Nanomedicine and Biotechnology
Volume9
Issue number2
DOIs
StatePublished - Jan 1981
Externally publishedYes

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