TY - JOUR
T1 - H blood group detection by the L-fucose binding lectin of the green marine alga Ulva lactuca
AU - Gilboa-Garber, Nechama
AU - Citronbaum, Rachel
AU - Levene, Cyril
AU - Sela, Ruth
N1 - Funding Information:
This research was supported by a grant from Bar-Ilan University research authorities. The authors thank Mrs. D. Radin for the skilful printing of the manuscript.
PY - 1988
Y1 - 1988
N2 - Extracts of the green marine alga Ulva lactuca collected along the seashore of Tel-Aviv exhibit hemagglutinating activity towards papain-treated human erythrocytes. This hemagglutinating activity was shown to be inhibited by L-fucose and EDTA, and to be relatively resistant to heating at 60°C, while sensitive to low pH. Like the lectin of Ulex europeus, the Ulva lectin exhibits blood group H specificity. It agglutinates most strongly erythrocytes of blood group 0(H) followed by B > A > AB. A2 and A2B erythrocytes are agglutinated by it considerably more strongly than A1 and A1B respectively. Bombay 0(hh) type erythrocytes are almost non-reactive. The lectin can be stored at -20°C for years.
AB - Extracts of the green marine alga Ulva lactuca collected along the seashore of Tel-Aviv exhibit hemagglutinating activity towards papain-treated human erythrocytes. This hemagglutinating activity was shown to be inhibited by L-fucose and EDTA, and to be relatively resistant to heating at 60°C, while sensitive to low pH. Like the lectin of Ulex europeus, the Ulva lectin exhibits blood group H specificity. It agglutinates most strongly erythrocytes of blood group 0(H) followed by B > A > AB. A2 and A2B erythrocytes are agglutinated by it considerably more strongly than A1 and A1B respectively. Bombay 0(hh) type erythrocytes are almost non-reactive. The lectin can be stored at -20°C for years.
UR - http://www.scopus.com/inward/record.url?scp=0024207264&partnerID=8YFLogxK
U2 - 10.1016/0145-305X(88)90045-6
DO - 10.1016/0145-305X(88)90045-6
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C2 - 3208955
AN - SCOPUS:0024207264
SN - 0145-305X
VL - 12
SP - 695
EP - 705
JO - Developmental and Comparative Immunology
JF - Developmental and Comparative Immunology
IS - 4
ER -
