Gut microbes and host behavior: The forgotten members of the gut-microbiome

Ariel Weiner, Sondra Turjeman, Omry Koren

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


The gut microbiota refers to an entire population of microorganisms that colonize the gut. This community includes viruses, prokaryotes (bacteria and archaea), and eukaryotes (fungi and parasites). Multiple studies in the last decades described the significant involvement of gut bacteria in gut-brain axis communication; however, the involvement of other members of the gut microbiota has been neglected. Recent studies found that these ‘forgotten’ members of the gut microbiota may also have a role in gut-brain communication, although it is still unclear whether they have a direct effect on the brain or if their effects are mediated by gut bacteria. Here, we provide concrete suggestions for future research to tease out mechanisms of the microbiota-gut-brain axis.

Original languageEnglish
Article number109453
StatePublished - 1 Apr 2023

Bibliographical note

Funding Information:
OK is supported by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (Grant agreement ERC-2020-COG No. 101001355 ).

Publisher Copyright:
© 2023 Elsevier Ltd


  • Archaeome
  • Bacteriome
  • Gut-brain axis
  • Microbiome
  • Mycobiome
  • Parasitome
  • Virome


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