TY - JOUR
T1 - Growth patterns in children with intrauterine growth retardation and their correlation to neurocognitive development
AU - Fattal-Valevski, Aviva
AU - Toledano-Alhadef, Hagit
AU - Leitner, Yael
AU - Geva, Ronny
AU - Eshel, Rina
AU - Harel, Shaul
PY - 2009/7
Y1 - 2009/7
N2 - The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for height between 1 and 2 years of age was significantly higher than the catch-up for weight (P < .001). The cognitive outcome at 9 to 10 years correlated with head circumference at all ages. The neurodevelopmental outcome at 9 to 10 years correlated with weight at all ages. Correlation with head circumference was more significant with IQ, while with weight it was stronger with the neurodevelopmental score. Height at 1 year was a significant predictor for IQ and neurodevelopmental outcome at 9 to 10 years. These findings are of distinct importance for prediction of subsequent neurodevelopmental outcome in children with intrauterine growth retardation.
AB - The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for height between 1 and 2 years of age was significantly higher than the catch-up for weight (P < .001). The cognitive outcome at 9 to 10 years correlated with head circumference at all ages. The neurodevelopmental outcome at 9 to 10 years correlated with weight at all ages. Correlation with head circumference was more significant with IQ, while with weight it was stronger with the neurodevelopmental score. Height at 1 year was a significant predictor for IQ and neurodevelopmental outcome at 9 to 10 years. These findings are of distinct importance for prediction of subsequent neurodevelopmental outcome in children with intrauterine growth retardation.
KW - Head circumference
KW - Height
KW - Intrauterine growth retardation
KW - Outcome
KW - Weight
UR - http://www.scopus.com/inward/record.url?scp=67949083638&partnerID=8YFLogxK
U2 - 10.1177/0883073808331082
DO - 10.1177/0883073808331082
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C2 - 19617460
AN - SCOPUS:67949083638
SN - 0883-0738
VL - 24
SP - 846
EP - 851
JO - Journal of Child Neurology
JF - Journal of Child Neurology
IS - 7
ER -