Graphdiyne Quantum Dots for H2O2 and Dopamine Detection

Syed Rahin Ahmed, Ana Gomez Cardoso, Herlys Viltres Cobas, Poushali Das, Aicheng Chen, Seshasai Srinivasan, Amin Reza Rajabzadeh

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The fluorescence and nanozymatic nature of quantum dots (QDs) in a single entity provide an excellent opportunity for the development of sensitive fluorescence and colorimetric biosensing and bioimaging approaches. Herein, the hydrothermal synthesis method of fluorescent graphdiyne quantum dots (GDY QDs) from graphdiyne sheets is presented. This research reports, for the first time, the nanozymatic activity of GDY QDs besides their conventional fluorescent nature, which catalyzes the oxidation of H2O2through the peroxidase biomimetic nature and enables detection of H2O2and dopamine. The peaks of the ultraviolet-visible (UV-vis) spectrum and the fluorescence emission of GDY QDs are located at 395 and 450 nm, respectively. The X-ray photoelectron spectroscopic (XPS) results reveal that GDY and GDY QDs have similar carbon skeletons. Moreover, the intensity of C-O and C═O peaks in GDY QDs is stronger than that of GDY, suggesting the successful surface oxidation of GDY, which is crucial for hydrophilicity and catalytic activity. Kinetic analysis reveals that as-synthesized GDY QDs exhibit Michaelis-Menten kinetic behavior. The terephthalic acid and DPPH test confirms the hydroxyl radical formation and scavenging nature of GDY QDs, playing a significant role in enhancing the nanozymatic activity. The biomimetic nature of GDY QDs is applied for H2O2and dopamine detection, and limit of detection (LOD) values of 0.13 and 8.65 μM are obtained for H2O2and dopamine, respectively. The findings of this study will open a door to the development of carbon-based nanocrystals with an enzyme-mimicking nature that can lead to the development of analytical approaches, in particular, colorimetric nanobiosensors.

Original languageEnglish
Pages (from-to)8434-8443
Number of pages10
JournalACS Applied Nano Materials
Volume6
Issue number10
DOIs
StatePublished - 26 May 2023
Externally publishedYes

Bibliographical note

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© 2023 American Chemical Society. All rights reserved.

Keywords

  • HO
  • colorimetric method
  • dopamine
  • graphdiyne quantum dots
  • nanozyme

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