Abstract
Aqueous initiators for continuous activator regeneration atom transfer radical polymerization (ICAR ATRP) was applied to graft well defined acrylamide, N,N-dimethylacrylamide and N-vinylimidazole homo and block copolymers from a model protein initiator (bovine serum albumin (BSA)) under bio-relevant conditions. Using N-vinylimidazole as a ligand catalytic biohybrid nanoparticles were prepared by loading palladium into a block copolymer of poly(N-vinylimidazole)-b-poly(oligo(ethylene oxide) acrylate) grafted from BSA. The protein-polymer biohybrid catalyst successfully catalyzes Suzuki-Miyaura couplings in aqueous media under aerobic conditions.
| Original language | English |
|---|---|
| Pages (from-to) | 3992-3998 |
| Number of pages | 7 |
| Journal | Polymer Chemistry |
| Volume | 8 |
| Issue number | 27 |
| DOIs | |
| State | Published - 21 Jul 2017 |
| Externally published | Yes |
Bibliographical note
Publisher Copyright:©2017 The Royal Society of Chemistry.
Funding
We gratefully acknowledge The Army Research Office (Grant W911NF-17-1-0015) Young Investigator Program and the Neuroscience Institute at AHN for funding NMR measurements and instrumentation at CMU which was partially supported by NSF (CHE-0130903 and CHE-1039870). The MALDI-TOF data were collected using instrumentation purchased with NSF grant award CHE0839233.
| Funders | Funder number |
|---|---|
| National Science Foundation | CHE-1039870, CHE-0130903, CHE0839233 |
| Army Research Office | W911NF-17-1-0015 |
| Carnegie Mellon University | |
| Neuroscience Institute, University of Tennessee |