TY - JOUR
T1 - Gold-palladium nanoparticles aided electrochemically reduced graphene oxide sensor for the simultaneous estimation of lomefloxacin and amoxicillin
AU - Kumar, Neeraj
AU - Rosy,
AU - Goyal, Rajendra N.
N1 - Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - A gold-palladium nanoparticles decorated electrochemically reduced graphene oxide (AuNP-PdNP-ErGO) modified, glassy carbon sensor has been developed for the individual and simultaneous determination of lomefloxacin (LMF) and amoxicillin (AMX). A new sensing platform exploiting the beneficial interaction of gold, palladium and ErGO has been prepared involving a one-step electrochemical process, and is characterized using Field Emission Scanning Electron Microscopy, elemental mapping, Transmission Electron Microscopy, Raman, X-ray diffraction and Electrochemical Impedance Spectroscopy. The calibration curves for LMF and AMX have been constructed using square wave voltammetry and exhibited a linear response in the concentration range of 4–500 μM and 30–350 μM respectively. The sensitivity and limit of detection were 0.0759 μA/μM and 81 nM, 0.0376 μA/μM and 9 μM for LMF and AMX respectively. The proposed protocol was successfully applied for testing the presence of LMF and AMX in the complex matrix like urine and in the solutions containing excess of potentially interfering substances like ascorbic acid, uric acid, hypoxanthine etc.
AB - A gold-palladium nanoparticles decorated electrochemically reduced graphene oxide (AuNP-PdNP-ErGO) modified, glassy carbon sensor has been developed for the individual and simultaneous determination of lomefloxacin (LMF) and amoxicillin (AMX). A new sensing platform exploiting the beneficial interaction of gold, palladium and ErGO has been prepared involving a one-step electrochemical process, and is characterized using Field Emission Scanning Electron Microscopy, elemental mapping, Transmission Electron Microscopy, Raman, X-ray diffraction and Electrochemical Impedance Spectroscopy. The calibration curves for LMF and AMX have been constructed using square wave voltammetry and exhibited a linear response in the concentration range of 4–500 μM and 30–350 μM respectively. The sensitivity and limit of detection were 0.0759 μA/μM and 81 nM, 0.0376 μA/μM and 9 μM for LMF and AMX respectively. The proposed protocol was successfully applied for testing the presence of LMF and AMX in the complex matrix like urine and in the solutions containing excess of potentially interfering substances like ascorbic acid, uric acid, hypoxanthine etc.
KW - Amoxicillin
KW - AuNPs
KW - Lomefloxacin
KW - Nano palladium
KW - Reduced graphene oxide
KW - Voltammetry
UR - http://www.scopus.com/inward/record.url?scp=85006014405&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2016.12.025
DO - 10.1016/j.snb.2016.12.025
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AN - SCOPUS:85006014405
SN - 0925-4005
VL - 243
SP - 658
EP - 668
JO - Sensors and Actuators, B: Chemical
JF - Sensors and Actuators, B: Chemical
ER -