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Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study

  • BLEND Study Collaborative Group
  • Duke University
  • University Hospitals of Derby and Burton NHS Foundation Trust
  • The University of Sydney
  • Barts Health NHS Trust
  • Advocate Health Care
  • Dr. Ram Manohar Lohia Hospital
  • Betsi Cadwaladr University Health Board
  • Dartford and Gravesham NHS Trust
  • Centro Hospitalar Universitário de Lisboa Central
  • Helwan University
  • Al-Basheer Hospital
  • Alfaisal University
  • Gharyan Central Hospital
  • Prince Sattam Bin Abdulaziz University
  • Aleppo Private Hospital
  • King Saud University
  • Bedfordshire Hospitals NHS Foundation Trust
  • Ain Shams University
  • Pamukkale University
  • Cantacuzino Clinical Hospital
  • Carretera Nacional 6501 Col La Estanzuela
  • University of Rome Tor Vergata
  • Dr. Sulaiman Alhabib Hospital
  • IRCCS Istituto Clinico Humanitas - Rozzano (Milano)
  • Çam & amp;Sakura City Hospital
  • Center of Excellence for the Study and Treatment of Obesity and Diabetes
  • King Saud Medical City
  • University of Verona
  • The First Affiliated Hospital of Jinan University
  • Najjar Hospital
  • University of Tripoli
  • University of Sunderland
  • Holy Family Hospital
  • Bar-Ilan University
  • University of Rochester
  • Al-Azhar University
  • ASL Roma 2
  • Hospital Regional de Alta Especialidad del Bajio
  • University of Bari
  • Ministry of Health, Turkey
  • University of Oklahoma
  • University of Patras
  • University of Naples Federico II
  • San Marco Hospital GSD
  • Azerbaycan Tibb Universiteti
  • Université Paris Cité
  • Inova Fair Oaks Hospital
  • Hospital Lusíadas Amadora
  • Nisantasi Universitesi
  • Evagelismos Hospital
  • University of Foggia
  • Türkçapar Bariatrics
  • Hospital General Tlahuac
  • Imperial College London
  • University of Birmingham
  • University Hospitals Birmingham NHS Foundation Trust

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: No robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures. Objectives: The objective of this study is to collect a 30-day mortality and morbidity of primary BMS combined with cholecystectomy, ventral hernia repair, or hiatal hernia repair. Setting: This is as an international, multicenter, prospective, and observational audit of patients undergoing primary BMS combined with one or more additional procedures. Methods: The audit took place from January 1 to June 30, 2022. A descriptive analysis was conducted. A propensity score matching analysis compared the BLEND study patients with those from the GENEVA cohort to obtain objective evaluation between combined procedures and primary BMS alone. Results: A total of 75 centers submitted data on 1036 patients. Sleeve gastrectomy was the most commonly primary BMS (N = 653, 63%), and hiatal hernia repair was the most commonly concomitant procedure (N = 447, 43.1%). RYGB accounted for the highest percentage (20.6%) of a 30-day morbidity, followed by SG (10.5%). More than one combined procedures had the highest morbidities among all combinations (17.1%). Out of overall 134 complications, 129 (96.2%) were Clavien-Dindo I–III, and 4 were CD V. Patients who underwent a primary bariatric surgery combined with another procedure had a pronounced increase in a 30-day complication rate compared with patients who underwent only BMS (12.7% vs. 7.1%). Conclusion: Combining BMS with another procedure increases the risk of complications, but most are minor and require no further treatment. Combined procedures with primary BMS is a viable option to consider in selected patients following multi-disciplinary discussion. Graphical Abstract: (Figure presented.)

Original languageEnglish
Pages (from-to)4152-4165
Number of pages14
JournalObesity Surgery
Volume34
Issue number11
Early online date13 Jun 2024
DOIs
StatePublished - Nov 2024
Externally publishedYes

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Combined procedures
  • Concomitant cholecystectomy
  • Concomitant hiatal hernia repair
  • Concomitant ventral hernia repair
  • Primary bariatric and metabolic surgery

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