Abstract
Gliosarcoma is a rare malignant, biphasic brain tumor composed of glioblastoma multiforme and sarcomatous components. Various types of sarcomatous differentiation are described in this tumor: fibrosarcomatous, malignant fibrous histiocytoma-like, chondrosarcomatous and osteosarcomatous types. We report an extremely unusual variant of liposarcomatous differentiation in gliosarcoma in 72-year-old woman. Fat cells were presented by atypical multivacuolar and monovacuolar lipoblasts, stained positive for S100. p53 that was positive in both glial and mesenchymal cells of the tumor were negative in the lipoblasts. To the best of our knowledge, this is the first report in the literature of liposarcomatous differentiation in gliosarcoma.
| Original language | English |
|---|---|
| Pages (from-to) | 381-384 |
| Number of pages | 4 |
| Journal | Archives of Pathology and Laboratory Medicine |
| Volume | 130 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 2006 |
| Externally published | Yes |
Bibliographical note
Funding Information:The RETUBES study is a prospective, multicenter observational study of a cohort of patients diagnosed with TB in Spain between January 1, 2010 and December 31, 2011, in whom MT was isolated and DST carried out. The study was designed by the Comprehensive Program for Research in Tuberculosis (PII-TB) of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR), and offered to all its members with the support of the PII-TB infrastructure and a SEPAR 2008 research grant.