Gliosarcoma with liposarcomatous differentiation: The new member of the lipid-containing brain tumors family: The new member of the lipid-containing brain tumors family

Eugene Vlodavsky, Marius Konstantinesku, Jean F. Soustiel

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Gliosarcoma is a rare malignant, biphasic brain tumor composed of glioblastoma multiforme and sarcomatous components. Various types of sarcomatous differentiation are described in this tumor: fibrosarcomatous, malignant fibrous histiocytoma-like, chondrosarcomatous and osteosarcomatous types. We report an extremely unusual variant of liposarcomatous differentiation in gliosarcoma in 72-year-old woman. Fat cells were presented by atypical multivacuolar and monovacuolar lipoblasts, stained positive for S100. p53 that was positive in both glial and mesenchymal cells of the tumor were negative in the lipoblasts. To the best of our knowledge, this is the first report in the literature of liposarcomatous differentiation in gliosarcoma.
Original languageEnglish
Pages (from-to)381-384
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Volume130
Issue number3
StatePublished - 1 Mar 2006

Fingerprint

Dive into the research topics of 'Gliosarcoma with liposarcomatous differentiation: The new member of the lipid-containing brain tumors family: The new member of the lipid-containing brain tumors family'. Together they form a unique fingerprint.

Cite this