Geroscience in the age of COVID-19

Nir Barzilai; James C. Appleby; Steven N. Austad; Ana Maria Cuervo; Matt Kaeberlein; Christian Gonzalez-Billault; Stephanie Lederman; Ilia Stambler; Felipe Sierra

doi:10.14336/AD.2020.0629

Geroscience in the age of COVID-19

Nir Barzilai, James C. Appleby, Steven N. Austad, Ana Maria Cuervo, Matt Kaeberlein, Christian Gonzalez-Billault, Stephanie Lederman, Ilia Stambler, Felipe Sierra

Research output: Contribution to journal › Review article › peer-review

25 Scopus citations

Abstract

The data on COVID-19 is clear on at least one point: Older adults are most vulnerable to hospitalization, disability and death following infection with the novel coronavirus. Therefore, therapeutically addressing degenerative aging processes as the main risk factors appears promising for tackling the present crisis and is expected to be relevant when tackling future infections, epidemics and pandemics. Therefore, utilizing a geroscience approach, targeting aging processes to prevent multimorbidity, via initiating broad clinical trials of potential geroprotective therapies, is recommended.

Original language	English
Pages (from-to)	725-729
Number of pages	5
Journal	Aging and Disease
Volume	11
Issue number	4
DOIs	https://doi.org/10.14336/AD.2020.0629
State	Published - Jul 2020
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2020 Barzilai N, et al.

Funding

The scientific Director of the American federation for Aging research (NB), the Nathan Shock Center of Excellence for the Biology of Aging P30AG038072 (NB), American Federation for Aging Research (SM), and Glenn Center for the Biology of Human Aging Paul Glenn Foundation Grant (NB).

Funders	Funder number
Glenn Center for the Biology of Human Aging Paul Glenn Foundation
Nathan Shock Center of Excellence for the Biology of Aging	P30AG038072
National Institute on Aging	RF1AG054108
AMERICAN FEDERATION FOR AGING RESEARCH

Keywords

Aging biomarkers
COVID-19
Geroprotectors
Geroscience
Immunosenescence

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10.14336/AD.2020.0629

Cite this

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abstract = "The data on COVID-19 is clear on at least one point: Older adults are most vulnerable to hospitalization, disability and death following infection with the novel coronavirus. Therefore, therapeutically addressing degenerative aging processes as the main risk factors appears promising for tackling the present crisis and is expected to be relevant when tackling future infections, epidemics and pandemics. Therefore, utilizing a geroscience approach, targeting aging processes to prevent multimorbidity, via initiating broad clinical trials of potential geroprotective therapies, is recommended.",

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AU - Lederman, Stephanie

AU - Stambler, Ilia

AU - Sierra, Felipe

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Geroscience in the age of COVID-19

Abstract

Bibliographical note

Funding

Keywords

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