Genomic analysis at the single-cell level

Tomer Kalisky; Paul Blainey; Stephen R. Quake

doi:10.1146/annurev-genet-102209-163607

Genomic analysis at the single-cell level

Tomer Kalisky
, Paul Blainey
, Stephen R. Quake

Howard Hughes Medical Institute

Research output: Contribution to journal › Article › peer-review

192 Scopus citations

Abstract

Studying complex biological systems such as a developing embryo, a tumor, or a microbial ecosystem often involves understanding the behavior and heterogeneity of the individual cells that constitute the system and their interactions. In this review, we discuss a variety of approaches to single-cell genomic analysis.

Original language	English
Pages (from-to)	431-445
Number of pages	15
Journal	Annual Review of Genetics
Volume	45
DOIs	https://doi.org/10.1146/annurev-genet-102209-163607
State	Published - 2011
Externally published	Yes

Keywords

FACS
FISH
Gene expression
QPCR
Sequencing
Single cell

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10.1146/annurev-genet-102209-163607

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KW - FACS

KW - FISH

KW - Gene expression

KW - QPCR

KW - Sequencing

KW - Single cell

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Genomic analysis at the single-cell level

Abstract

Keywords

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