TY - JOUR
T1 - Gallstones in pregnancy and their complications
T2 - Postpartum acute pancreatitis and acute peritonitis
AU - Blum, Arnon
AU - Tatour, Imad
AU - Monir, Merei
AU - Khazim, Khalid
AU - Simsolo, Claudia
PY - 2005/11
Y1 - 2005/11
N2 - Pregnancy is associated with a heightened risk of gallstone formation because of increased bile lithogenicity as a result of a decline in the bile salt pool and elevations in serum and biliary cholesterol levels. Increased bile stasis caused by impaired gallbladder emptying is also thought to be a contributing factor. In the case of mildly symptomatic gallstones, conservative management is recommended. It is now agreed that aggressive endoscopic intervention for biliary disorders in pregnancy and in the postpartum period appears to decrease morbidity, mortality, and costs. Endoscopy offers a safer, more effective treatment alternative to prolonged medical management and traditional surgical intervention during pregnancy and in the postpartum period.
AB - Pregnancy is associated with a heightened risk of gallstone formation because of increased bile lithogenicity as a result of a decline in the bile salt pool and elevations in serum and biliary cholesterol levels. Increased bile stasis caused by impaired gallbladder emptying is also thought to be a contributing factor. In the case of mildly symptomatic gallstones, conservative management is recommended. It is now agreed that aggressive endoscopic intervention for biliary disorders in pregnancy and in the postpartum period appears to decrease morbidity, mortality, and costs. Endoscopy offers a safer, more effective treatment alternative to prolonged medical management and traditional surgical intervention during pregnancy and in the postpartum period.
UR - http://www.scopus.com/inward/record.url?scp=27744524362&partnerID=8YFLogxK
U2 - 10.1016/j.ejim.2005.03.005
DO - 10.1016/j.ejim.2005.03.005
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AN - SCOPUS:27744524362
SN - 0953-6205
VL - 16
SP - 473
EP - 476
JO - European Journal of Internal Medicine
JF - European Journal of Internal Medicine
IS - 7
ER -