Further purification and characterization of a thermophilic rennet

Shoshana Laxer, Alex Pnsky, Benjamin Bartoov

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Further work on a thermophilic rennet synthesized by a thermophilic actinomycete is reported. It was produced by growth in fermentor of 50‐or‐200‐L volume and was purified by membrane filtration of a cell‐free supernatant and then molecular filtration and ion exchange chromatography. Its stability under various conditions was determined: The enzyme is a true rennet requiring calcium ions for activity. Experiment shows that it resembles neither pepsin, trypsin, nor chymotrypsin. It is freeze‐labile with a molecular weight of 9700 from amino acid composition. When skim milk powder was added to the growth medium, a rennet with different properties was obtained.

Original languageEnglish
Pages (from-to)2483-2492
Number of pages10
JournalBiotechnology and Bioengineering
Volume23
Issue number11
DOIs
StatePublished - Nov 1981

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