Field outbreak strains of serotype O foot-and-mouth disease virus from India with a deletion in the immunodominant βG-βH loop of the VP1 protein

Biswajit Das, Aniket Sanyal, Saravanan Subramaniam, Jajati K. Mohapatra, Bramhadev Pattnaik

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Foot-and-mouth disease virus serotype O accounts for around 80 % of the outbreaks in India. Although Indian serotype O isolates belongs to the ME-SA topotype, circulation of different lineages has been noted. After its emergence in the year 2001, the 'Ind2001' lineage outcompeted the PanAsia lineage in causing serotype O outbreaks in the year 2009. Three isolates had an amino acid deletion at position 139 in the VP1 coding region and grouped with the 'Ind2001' lineage. The currently used Indian vaccine strain of serotype O covers all of the field isolates antigenically.

Original languageEnglish
Pages (from-to)1967-1970
Number of pages4
JournalArchives of Virology
Volume157
Issue number10
DOIs
StatePublished - Oct 2012
Externally publishedYes

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