Fatty Pancreas Represents a Risk Factor for Acute Pancreatitis: A Pilot Study

Wisam Sbeit, Tawfik Khoury

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Objectives Fatty pancreas (FP), previously believed to be without clinical significance, recently has been shown to be associated with comorbid diseases. We aimed to explore whether FP predispose to acute pancreatitis. Methods Patients who underwent endoscopic ultrasound for hepatobiliary indications were included. Patients with pathological pancreato-biliary findings other than FP were excluded. The cohort was divided into patients with a history of pancreatitis (within 6 months of endoscopic ultrasound, group A) and patients without (group B). Results Overall, 189 patients were included. Sixty-one (32.3%) patients were in group A, and 128 (67.7%) patients were in group B. The average age in group A was 55.5 (standard deviation, 17.7) versus 58.5 (standard deviation, 13.5) in group B. The prevalence of FP in group A (37.7%) was higher compared with group B (4.7%) (P = 0.001). On univariate analysis, FP showed significant correlation with a history of acute pancreatitis [odds ratio (OR), 5.14, P = 0.006] and hyperlipidemia (OR, 4.19; P = 0.002). On multivariate analysis, FP remained significantly associated with a history of acute pancreatitis after stratification for obesity and hyperlipidemia (OR, 10.78; 95% confidence interval, 3.75-30.89; P < 0.0001). Conclusions Fatty pancreas was associated with acute pancreatitis. Clinicians should be aware of this association.

Original languageEnglish
Pages (from-to)990-993
Number of pages4
Issue number7
StatePublished - 1 Aug 2021

Bibliographical note

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.


  • fatty pancreas
  • pancreas
  • pancreatitis
  • risk factor


Dive into the research topics of 'Fatty Pancreas Represents a Risk Factor for Acute Pancreatitis: A Pilot Study'. Together they form a unique fingerprint.

Cite this