Farnesyl-homogentisic acid derivatives from Otoba parvifolia

A. Gilberto Ferreira, Mario Motidome, Otto R. Gottlieb, João B. Fernandes, Paulo C. Vieira, Miriam Cojocaru, Hugo E. Gottlieb

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The seeds of Otoba parvifolia contain six novel compounds, apparently derived from homogentisic acid, including 3-farnesyl-2,5-dihydroxybenzaldehyde, 2-(1′-farnesyl-2′-hydroxy-5′-oxocyclohex-3′-en-1′-yl)-acetic acid lactone, 3-(1′-farnesyl-2′-hydroxy-4′-oxocyclopentan-1′-yl)-3-methoxy (and ethoxy) propanoic acid lactones and methyl esters. New spectral evidence obtained for the known furofuran lignans xanthoxylol and phillygenol, isolated from the same source, was used as a basis for comments on the structure of horsfieldin.

Original languageEnglish
Pages (from-to)579-583
Number of pages5
Issue number2
StatePublished - 1989


  • Myristicaceae
  • Otoba parvifolia
  • farnesyl derivatives
  • homogentisic acid pathway.
  • oxocyclohexenylacetic acid
  • oxocyclopentanylpropionic acids
  • phillygenol
  • xanthoxylol


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