Factors associated with recurrence of tracheoesophageal fistula

Vered Nir, Michal Gur, Yazeed Toukan, Fahed Hakim, Arcadi Vachyan, Lea Bentur

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background: Recurrence of tracheoesophageal fistula (TEF) is reported in 8–20% patients. Factors that may influence recurrence of fistula beyond the postoperative period are not clear. Objectives: To evaluate possible factors associated with recurrence of TEF beyond the immediate postoperative period. Methods: A single center, retrospective comparison of patients with and without recurrence of TEF was conducted. Medical records of patients previously operated for TEF who were followed in our pediatric pulmonary institute between January 2007 and December 2016 were reviewed. Results: The medical records of 74/77 patients previously operated for TEF were evaluated. Nine patients (12%) had a recurrence of TEF and 65 did not. These groups had similar age and gender distribution and similar prevalence of VACTERL association. In addition, they had similar length of atretic gap, rates of thoracoscopic surgery, rates of prolonged need for respiratory assistance post-surgery, and frequency of gastrointestinal symptoms. Notably, the patients who had recurrent TEF had significantly more hospitalizations for respiratory symptoms (P = 0.011) and significantly more episodes of clinical bronchiolitis per patient (P < 0.0001). In addition, the patients with recurrent TEF had significantly more episodes of positive polymerase chain reaction for viruses (P = 0.009). Conclusions: Hospitalizations for respiratory symptoms as well as clinical and/or viral bronchiolitis are associated with recurrence of TEF. Even though cause and effect cannot be established, these patients should undergo meticulous evaluation for the possibility of recurrence of TEF.

Original languageEnglish
Pages (from-to)687-690
Number of pages4
JournalIsrael Medical Association Journal
Volume20
Issue number11
StatePublished - Nov 2018
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2018, Israel Medical Association. All rights reserved.

Keywords

  • Bronchiolitis
  • Tracheoesophageal fistula (TEF)

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