Facile Synthesis of Oxime Amino Ethers via Lewis Acid Catalyzed S N 2-Type Ring Opening of Activated Aziridines with Aryl Aldehyde Oximes

Aditya Bhattacharyya, Subhomoy Das, Navya Chauhan, Pronay K. Biswas, Manas K. Ghorai

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

A simple strategy to access a wide range of substituted oxime amino ethers in good to high yields via Lewis acid catalyzed S N 2-type ring opening of activated aziridines with aryl aldehyde oximes is reported.

Original languageEnglish
Pages (from-to)708-712
Number of pages5
JournalSynlett
Volume31
Issue number7
DOIs
StatePublished - 22 Apr 2020
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2020 Georg Thieme Verlag. All rights reserved.

Funding

M.K.G. is thankful to the Department of Science and Technology (DST), India for financial support. A.B. thanks the Council of Scientific and Industrial Research (CSIR), New Delhi, India for a research fellowship. S.D. and N.C. thank University Grants Commission (UGC), New Delhi, India for Senior Research Fellowships. DepartmentofScienceandTechnology(DST)()IndianInstituteofChemicalBiology()

FundersFunder number
Department of Science and Technology, Ministry of Science and Technology, India
Council of Scientific and Industrial Research, India
University Grants Commission

    Keywords

    • Lewis acid catalyst
    • S 2-type ring opening
    • aziridine
    • oxime
    • oxime ether
    • stereoselectivity

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