Facile construction of substituted bicyclo [n.3.1] alkanones and the synthesis of a 12-membered dilactone via a new functionalized pentadienoic ester

Eugene Ghera; Namakkal Govind Ramesh; Avital Laxer; Alfred Hassner

doi:10.1016/0040-4039(94)02470-v

Facile construction of substituted bicyclo [n.3.1] alkanones and the synthesis of a 12-membered dilactone via a new functionalized pentadienoic ester

Eugene Ghera, Namakkal Govind Ramesh, Avital Laxer, Alfred Hassner

Department of Chemistry

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

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Abstract

4-Hydroxymethyl-2,4-pentadienoate was effectively synthesized and used for a synthetic entry to keto bridged bicyclo [n.3.1] alkanones and for the synthesis of a 12-membered macrodilide characterized by two trans double bonds, part of two vinylogous α-methylene lactone units.

Original language	English
Pages (from-to)	1333-1336
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	8
DOIs	https://doi.org/10.1016/0040-4039(94)02470-v
State	Published - 20 Feb 1995

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abstract = "4-Hydroxymethyl-2,4-pentadienoate was effectively synthesized and used for a synthetic entry to keto bridged bicyclo [n.3.1] alkanones and for the synthesis of a 12-membered macrodilide characterized by two trans double bonds, part of two vinylogous α-methylene lactone units.",

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AU - Govind Ramesh, Namakkal

AU - Laxer, Avital

AU - Hassner, Alfred

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AB - 4-Hydroxymethyl-2,4-pentadienoate was effectively synthesized and used for a synthetic entry to keto bridged bicyclo [n.3.1] alkanones and for the synthesis of a 12-membered macrodilide characterized by two trans double bonds, part of two vinylogous α-methylene lactone units.

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Facile construction of substituted bicyclo [n.3.1] alkanones and the synthesis of a 12-membered dilactone via a new functionalized pentadienoic ester

Abstract

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