Facile construction of substituted bicyclo [n.3.1] alkanones and the synthesis of a 12-membered dilactone via a new functionalized pentadienoic ester

Eugene Ghera, Namakkal Govind Ramesh, Avital Laxer, Alfred Hassner

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

4-Hydroxymethyl-2,4-pentadienoate was effectively synthesized and used for a synthetic entry to keto bridged bicyclo [n.3.1] alkanones and for the synthesis of a 12-membered macrodilide characterized by two trans double bonds, part of two vinylogous α-methylene lactone units.

Original languageEnglish
Pages (from-to)1333-1336
Number of pages4
JournalTetrahedron Letters
Volume36
Issue number8
DOIs
StatePublished - 20 Feb 1995

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