Extraction of the absorption coefficient of cylindrical tissue from a single wavelength based on the full scattering profile

Idit Feder, Hamootal Duadi, Dror Fixler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Sensing physiological parameters by optical methods is very common because they are simple to use, they do not hurt the patient and they provide a real-time measurement. These parameters, such as oxygen saturation, are based on detection of light absorption through the tissue. The existing method uses multiple wavelengths to extract the absorption coefficient. However, the optical pathlength depends on the wavelength. Hence, the use of different light sources, which propagate through the tissue in different pathlengths, adds an inherent error to the calculation of the absorption coefficient. We suggest a new optical method for extracting the absorption coefficient of cylindrical tissues by a single wavelength. The method uses one wavelength only and therefore does not suffer from inherent errors. Our calculation is based on the iso-pathlength (IPL) point that we previously found. This phenomenon was discovered using a new characterization of cylindrical tissues, the full scattering profile, which is the light intensity distribution on the surface. In the IPL point, the light intensity remains constant for different scattering coefficients. We will use the light intensity measurement in this point in order to quantitatively extract the absorption coefficient.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII
EditorsDror Fixler, Ewa M. Goldys, Sebastian Wachsmann-Hogiu
PublisherSPIE
ISBN (Electronic)9781510632714
DOIs
StatePublished - 2020
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII 2020 - San Francisco, United States
Duration: 2 Feb 20203 Feb 2020

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11254
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII 2020
Country/TerritoryUnited States
CitySan Francisco
Period2/02/203/02/20

Bibliographical note

Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

Keywords

  • Monte Carlo
  • Scattering
  • Tissue absorption

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