Imaging inside a turbid media is range limited. In contrast, sensing the medium's optical properties is possible in larger depths using the iterative multi-plane optical properties extraction (IMOPE) technique. It analyzes the reemitted light phase image reconstructed from the iterative multi-plane Gerchberg-Saxton (GS) algorithm. The root mean square (RMS) of the phase yields two graphs with opposite behaviors, that cross each other in μ's,cp. The graphs enable the extraction of the reduced scattering coefficient, μs', of the measured tissue. The IMOPE was originally developed for illumination of red wavelength and for biological applications and was extended to the blue regime of the electromagnetic field, which is applicable for underwater research. In this work, we aim to extend the range of μs' detection by optical magnification. We use a modified diffusion theory and show how μ's,cp shifts with the varying magnification. The theoretical results were then tested experimentally, using agar-based phantoms with varying scatterings coefficients.
|Title of host publication||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX|
|Editors||Dror Fixler, Ewa M. Goldys, Sebastian Wachsmann-Hogiu|
|State||Published - 2022|
|Event||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX 2022 - Virtual, Online|
Duration: 20 Feb 2022 → 24 Feb 2022
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Conference||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX 2022|
|Period||20/02/22 → 24/02/22|
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Copyright © 2022 SPIE.
- Gerchberg-Saxton algorithm
- phase image
- reduced scattering coefficient