Extracting the reduced scattering coefficient in different optical magnifications in the blue regime: theory and experiments

Channa Shapira, Inbar Yariv, Hamootal Duadi, Dror Fixler

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Imaging inside a turbid media is range limited. In contrast, sensing the medium's optical properties is possible in larger depths using the iterative multi-plane optical properties extraction (IMOPE) technique. It analyzes the reemitted light phase image reconstructed from the iterative multi-plane Gerchberg-Saxton (GS) algorithm. The root mean square (RMS) of the phase yields two graphs with opposite behaviors, that cross each other in μ's,cp. The graphs enable the extraction of the reduced scattering coefficient, μs', of the measured tissue. The IMOPE was originally developed for illumination of red wavelength and for biological applications and was extended to the blue regime of the electromagnetic field, which is applicable for underwater research. In this work, we aim to extend the range of μs' detection by optical magnification. We use a modified diffusion theory and show how μ's,cp shifts with the varying magnification. The theoretical results were then tested experimentally, using agar-based phantoms with varying scatterings coefficients.

Original languageEnglish
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX
EditorsDror Fixler, Ewa M. Goldys, Sebastian Wachsmann-Hogiu
PublisherSPIE
ISBN (Electronic)9781510648234
DOIs
StatePublished - 2022
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX 2022 - Virtual, Online
Duration: 20 Feb 202224 Feb 2022

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11976
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX 2022
CityVirtual, Online
Period20/02/2224/02/22

Bibliographical note

Publisher Copyright:
Copyright © 2022 SPIE.

Keywords

  • Gerchberg-Saxton algorithm
  • phase image
  • reduced scattering coefficient

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