TY - JOUR
T1 - Expression of Active Human Interferon-β in Transgenic Plants
AU - Edelbaum, Orit
AU - Stein, Dana
AU - Holland, Neta
AU - Gafni, Yedidiah
AU - Livneh, Orna
AU - Novick, Daniela
AU - Rubinstein, Menachem
AU - Sela, Ilan
PY - 1992/12
Y1 - 1992/12
N2 - Tobacco plants were transformed with the human gene for interferon-β (IFN-β). Transformation was determined by the polymerase chain reaction (PCR), and expression was determined by Western blot analysis, by purifying the IFN from the transgenic plants, and by bioassays indicating its activity in human cells. Plants expressing IFN-β were self-pollinated. IFN-β-expressing progeny plants were selected and produced active IFN-β, indicating stable transformation.
AB - Tobacco plants were transformed with the human gene for interferon-β (IFN-β). Transformation was determined by the polymerase chain reaction (PCR), and expression was determined by Western blot analysis, by purifying the IFN from the transgenic plants, and by bioassays indicating its activity in human cells. Plants expressing IFN-β were self-pollinated. IFN-β-expressing progeny plants were selected and produced active IFN-β, indicating stable transformation.
UR - http://www.scopus.com/inward/record.url?scp=0026685945&partnerID=8YFLogxK
U2 - 10.1089/jir.1992.12.449
DO - 10.1089/jir.1992.12.449
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C2 - 1337755
AN - SCOPUS:0026685945
SN - 0197-8357
VL - 12
SP - 449
EP - 453
JO - Journal of Interferon Research
JF - Journal of Interferon Research
IS - 6
ER -