Exploring the role of the self in disgust-related psychopathologies

Uri Berger, David Anaki

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


While clinical research on disgust relies on nonclinical research, the framework of disgust as an immune mechanism is not as central in clinical research. The immune framework for disgust may be integrated into clinical research by acknowledging the role of the self as the critical element protected by the immune system. In this review, we offer the premise that at the center of all disgust-related behaviors, thoughts, and cognitions is an attempt to protect the self (i.e., “disgust is self-centered” or DISC). We offer evidence in support of DISC and explore the relevance of DISC to clinical research for several disgust-related psychopathologies (obsessive-compulsive disorder, posttraumatic stress disorder, anorexia nervosa, and self-disgust). We then offer future directions for DISC research into disgust-related psychopathologies.

Original languageEnglish
Pages (from-to)113-132
Number of pages20
JournalBulletin of the Menninger Clinic
Issue numberSA
StatePublished - 1 Mar 2023

Bibliographical note

Publisher Copyright:
(Copyright © 2023 The Menninger Foundation)


  • anorexia
  • disgust
  • immune system
  • obsessive-compulsive disorder
  • posttraumatic stress disorder
  • self


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