Exhaustion of motor cortex after head injury--revealed by transcranial magnetic stimulation

M. Elron, G. Levi, M. Trovnick, J. F. Soustiel, H. Hafner, A. Chistyakov, M. Feinsod

Research output: Contribution to journalArticlepeer-review


We evaluated the pattern of motor evoked potentials elicited by single-pulse and slow-rate (1 Hz) repetitive, transcranial, magnetic stimulation (RTMS) in minor head injuries. The motor response to a single magnetic stimulus in patients with minor head injury was characterized by a significantly higher threshold than in healthy subjects. However, central and peripheral motor conduction was normal in all patients. A stable pattern of MEP throughout the RTMS session was the most prominent feature in the control group. A progressive decrease in MEP amplitude and irregular alternation of large and very small MEPs over the course of RTMS was observed in minor head injury. The higher threshold of the motor response and the abnormal patterns of MEP behavior revealed by RTMS may reflect impaired excitability and enhanced exhaustion of the motor cortex in patients with minor head injuries, which improve with time.

Original languageEnglish
Pages (from-to)355-358, 419
Issue number5
StatePublished - 1 Mar 1999
Externally publishedYes


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