Abstract
Chimeric RNAs are generated by the fusion of the exons or introns of two genes. The generation of chimeric RNAs is important for the functional expansion of cells. Here, we describe the functional implications of chimeric RNAs for generating phenotypic plasticity from an evolutionary perspective.
| Original language | English |
|---|---|
| Pages (from-to) | 4-7 |
| Number of pages | 4 |
| Journal | Trends in Genetics |
| Volume | 38 |
| Issue number | 1 |
| Early online date | 24 Sep 2021 |
| DOIs | |
| State | Published - Jan 2022 |
Bibliographical note
Publisher Copyright:© 2021 Elsevier Ltd
Funding
We thank the Israeli Council for Higher Education for the PBC fellowship award to Dr Sumit Mukherjee under the category of outstanding postdoctoral researchers from China and India (2019–2021). We thank members of the Cancer Genomics and Biocomputing of Complex Diseases Lab for their discussions and comments on this paper.
| Funders |
|---|
| Council for Higher Education |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- cancer evolution
- chimeric RNA
- gene fusion
- phenotypic plasticity
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