TY - JOUR
T1 - Evolution on a smooth landscape
T2 - The role of bias
AU - Ridgway, Douglas
AU - Levine, Herbert
AU - Kessler, David A.
PY - 1998/1
Y1 - 1998/1
N2 - The role of mutational bias in evolution on a smooth landscape is investigated. We consider both a finite-length genome where the bias increases linearly with the fitness, and an infinite genome with a fixed bias. We present simulations of finite populations in a waiting time model, showing both the nonequilibrium dynamics and the equilibrium fitness distributions that are reached. We compute the equilibrium analytically in several cases, using approximate direct solution of the master equations and truncated hierarchies.
AB - The role of mutational bias in evolution on a smooth landscape is investigated. We consider both a finite-length genome where the bias increases linearly with the fitness, and an infinite genome with a fixed bias. We present simulations of finite populations in a waiting time model, showing both the nonequilibrium dynamics and the equilibrium fitness distributions that are reached. We compute the equilibrium analytically in several cases, using approximate direct solution of the master equations and truncated hierarchies.
KW - Birth/death processes
KW - Evolution
KW - Mean-field
KW - Population dynamics
UR - http://www.scopus.com/inward/record.url?scp=0031622486&partnerID=8YFLogxK
U2 - 10.1023/a:1023203818384
DO - 10.1023/a:1023203818384
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AN - SCOPUS:0031622486
SN - 0022-4715
VL - 90
SP - 191
EP - 210
JO - Journal of Statistical Physics
JF - Journal of Statistical Physics
IS - 1-2
ER -