Evolution on a smooth landscape: The role of bias

Douglas Ridgway, Herbert Levine, David A. Kessler

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The role of mutational bias in evolution on a smooth landscape is investigated. We consider both a finite-length genome where the bias increases linearly with the fitness, and an infinite genome with a fixed bias. We present simulations of finite populations in a waiting time model, showing both the nonequilibrium dynamics and the equilibrium fitness distributions that are reached. We compute the equilibrium analytically in several cases, using approximate direct solution of the master equations and truncated hierarchies.

Original languageEnglish
Pages (from-to)191-210
Number of pages20
JournalJournal of Statistical Physics
Issue number1-2
StatePublished - Jan 1998


  • Birth/death processes
  • Evolution
  • Mean-field
  • Population dynamics


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