Evidence for the existence of an IL-2 like lymphocyte growth promoting factor in a bony fish, Cyprinus carpio

Rachel R. Caspi, Ramy R. Avtalion

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Activity promoting the growth of carp T-like cells has been found in supernatants of mitogen (PHA)- and alloantigen (MLR)-stimulated carp leukocyte cultures. Activity level in culture supernatants was elevated by phorbol myristate acetate. Proliferation of carp T-like lymphoblasts was also promoted in the presence of Il-2-containing supernatants of mammalian origin. The significance of these findings is discussed.

Original languageEnglish
Pages (from-to)51-60
Number of pages10
JournalDevelopmental and Comparative Immunology
Volume8
Issue number1
DOIs
StatePublished - 1984

Bibliographical note

Funding Information:
ACKNOWLEDGEMENTSz Supported by Grant No. 01-509 from Bar-Ilan University, Grant No. QII from the National Council for Research and Development, Israel, and by the KGSS Geesthacht-Tesperhude, Germany. We wish to thank Mrs. Bluma Lederhendler for typing this manuscript.

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