Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system

Alexander Axelevitch; Vasilisa Akselevich

doi:10.1109/mfi.2015.7295830

Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system

Alexander Axelevitch, Vasilisa Akselevich

Department of Psychology

Holon Institute of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Oxytocin is one of the most prominent neuropeptides in mammalian, and in particular, human organisms. It is also prominently featured in neuropsychological and social-neurology research, due to its high involvement in a wide range of behavioral and physiological processes. One of the difficulties in measurement is the short lifetime of free molecules of Oxytocin. In our paper, we studied the possibility to measure and evaluate operatively the level and type of free neuropeptide molecules by non-invasive method. For this goal, we prepared the plasmonic-enhanced sensors used as the substrates for measurements. Such sensors consist of a single crystalline silicon bar coated by a nano-structured gold thin film and covered by a very thin dielectric passivating coating. The studied substance containing the neuropeptides will be delivered on the sensing surface and then, it will be exposed with the laser's light. A polarized optical signal reflected from the studied substance and expanded in the spectrum form will bring us the significant information about this substance.

Original language	English
Title of host publication	2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	334-338
Number of pages	5
ISBN (Electronic)	9781479977727
DOIs	https://doi.org/10.1109/mfi.2015.7295830
State	Published - 9 Oct 2015
Event	IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015 - San Diego, United States Duration: 14 Sep 2015 → 16 Sep 2015

Publication series

Name	IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems
Volume	2015-October

Conference

Conference	IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015
Country/Territory	United States
City	San Diego
Period	14/09/15 → 16/09/15

Bibliographical note

Publisher Copyright:
© 2015 IEEE.

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10.1109/mfi.2015.7295830

Cite this

Axelevitch, A., & Akselevich, V. (2015). Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system. In 2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015 (pp. 334-338). Article 7295830 (IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems; Vol. 2015-October). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/mfi.2015.7295830

Axelevitch, Alexander ; Akselevich, Vasilisa. / Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system. 2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 334-338 (IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems).

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abstract = "Oxytocin is one of the most prominent neuropeptides in mammalian, and in particular, human organisms. It is also prominently featured in neuropsychological and social-neurology research, due to its high involvement in a wide range of behavioral and physiological processes. One of the difficulties in measurement is the short lifetime of free molecules of Oxytocin. In our paper, we studied the possibility to measure and evaluate operatively the level and type of free neuropeptide molecules by non-invasive method. For this goal, we prepared the plasmonic-enhanced sensors used as the substrates for measurements. Such sensors consist of a single crystalline silicon bar coated by a nano-structured gold thin film and covered by a very thin dielectric passivating coating. The studied substance containing the neuropeptides will be delivered on the sensing surface and then, it will be exposed with the laser's light. A polarized optical signal reflected from the studied substance and expanded in the spectrum form will bring us the significant information about this substance.",

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Axelevitch, A & Akselevich, V 2015, Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system. in 2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015., 7295830, IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems, vol. 2015-October, Institute of Electrical and Electronics Engineers Inc., pp. 334-338, IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015, San Diego, United States, 14/09/15. https://doi.org/10.1109/mfi.2015.7295830

Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system. / Axelevitch, Alexander; Akselevich, Vasilisa.
2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 334-338 7295830 (IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems; Vol. 2015-October).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Axelevitch A, Akselevich V. Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system. In 2015 IEEE International Conference on Multisensor Fusion and lntegration for Intelligent Systems, MFI 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 334-338. 7295830. (IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems). doi: 10.1109/mfi.2015.7295830

Evaluation of the neuropeptides level using a surface enhanced mobile spectroscopy system

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