Evaluation of immunomodulator supplementation against chicken infectious anaemia virus induced altrerations in lymphoid organs and growth performance

The present investigation was undertaken to assess the protective potential of immunomodulators against chicken infectious anaemia virus (CIAV) induce alterations in lymphoid organs and productive performance in chicks. For the experimental study, total 120 SPF broiler chicks were divided into six groups with 20 chicks each. Vaccination against NCD and IBD was performed on day 1st and 12th, respectively of the study period. All the chicks of groups II to VI were infected with CIAV intramuscularly. The chicks of groups I and II served as healthy and infected controls, respectively during the study period. The chicks of group III to VI in addition received various immunomodulators and haematinic. The alterations induced by CIAV on lymphoid organs and weight gain and its amelioration by immunomodulator supplementation were recorded in experimental chicks at regular interval. Pathological alterations and reduced weight gain were recorded in all CIAV challenged chicks, however the intensity was less in immunomodulator supplemented groups. On the basis of above findings, it can be concluded that immunomodulator supplementation can be minimize the pathological alterations and weight gain reduction in CIAV infection.