Evaluation of a monoclonal antibody-based enzyme immunoassay for early detection of herpes simplex virus genital infection

J. Bornstein, E. Ben-Porath, M. Nizri, Y. Satinger, S. Sperber, H. Abramovici

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A monoclonal antibody-based enzyme immunoassay test for detection of herpes simplex virus (HSV) type-common antigen was evaluated in 40 women with vulvar lesion suspicious for genital HSV infection. The assay gave interpretable readings in 90% of the cases, with sensitivity and specificity of 100% and 92% respectively, a negative predictive value of 100%, and a positive predictive value of 75%. With a few limitations, the assay may be used for early diagnosis of genital HSV infection.

Original languageEnglish
Pages (from-to)445-448
Number of pages4
JournalIsrael Journal of Medical Sciences
Volume29
Issue number8
StatePublished - Aug 1993
Externally publishedYes

Keywords

  • Antigen
  • Diagnosis
  • Herpes simplex virus
  • Labor
  • Monoclonal antibody
  • Vulvar ulcer

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