Essential reactive intermediates in nucleoside chemistry: Cyclonucleoside cations

Anatoly M. Belostotskii; Elisheva Genizi; Alfred Hassner

doi:10.1039/c2ob25868d

Essential reactive intermediates in nucleoside chemistry: Cyclonucleoside cations

Anatoly M. Belostotskii, Elisheva Genizi, Alfred Hassner

Department of Chemistry

Bar-Ilan University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

DFT-based modeling as well as experimental examination of model keto nucleosides have revealed that high susceptibility of these compounds to acids is due to formation of intermediate cyclonucleoside cations of low energy. Theoretically established chemical structures of these previously overlooked intermediates explain the reaction courses for a cluster of nucleoside reactions.

Original language	English
Pages (from-to)	6624-6628
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	33
DOIs	https://doi.org/10.1039/c2ob25868d
State	Published - 7 Sep 2012

Access to Document

10.1039/c2ob25868d

Cite this

@article{f3404c547eba454eb50ff4ecd8ca4d6d,

title = "Essential reactive intermediates in nucleoside chemistry: Cyclonucleoside cations",

abstract = "DFT-based modeling as well as experimental examination of model keto nucleosides have revealed that high susceptibility of these compounds to acids is due to formation of intermediate cyclonucleoside cations of low energy. Theoretically established chemical structures of these previously overlooked intermediates explain the reaction courses for a cluster of nucleoside reactions.",

author = "Belostotskii, {Anatoly M.} and Elisheva Genizi and Alfred Hassner",

year = "2012",

month = sep,

day = "7",

doi = "10.1039/c2ob25868d",

language = "אנגלית",

volume = "10",

pages = "6624--6628",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "33",

}

TY - JOUR

T1 - Essential reactive intermediates in nucleoside chemistry

T2 - Cyclonucleoside cations

AU - Belostotskii, Anatoly M.

AU - Genizi, Elisheva

AU - Hassner, Alfred

PY - 2012/9/7

Y1 - 2012/9/7

N2 - DFT-based modeling as well as experimental examination of model keto nucleosides have revealed that high susceptibility of these compounds to acids is due to formation of intermediate cyclonucleoside cations of low energy. Theoretically established chemical structures of these previously overlooked intermediates explain the reaction courses for a cluster of nucleoside reactions.

AB - DFT-based modeling as well as experimental examination of model keto nucleosides have revealed that high susceptibility of these compounds to acids is due to formation of intermediate cyclonucleoside cations of low energy. Theoretically established chemical structures of these previously overlooked intermediates explain the reaction courses for a cluster of nucleoside reactions.

UR - http://www.scopus.com/inward/record.url?scp=84864619230&partnerID=8YFLogxK

U2 - 10.1039/c2ob25868d

DO - 10.1039/c2ob25868d

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 22805739

SN - 1477-0520

VL - 10

SP - 6624

EP - 6628

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 33

ER -

Essential reactive intermediates in nucleoside chemistry: Cyclonucleoside cations

Abstract

Access to Document

Other files and links

Fingerprint

Cite this