Enzymatic Screening of Microalgae as a Potential Source of Natural Antioxidants

Ritsuko Matsukawa, Zvy Dubinsky, Kazuyoshi Masaki, Toshifumi Takeuchi, Isao Karube

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations

    Abstract

    Extracts of over 100 species of microalgae both from nature and from laboratory cultures were screened for antioxidant activity. As an assay for antioxidant function, we examined the inhibition of the activity of two oxidizing enzymes, lipoxygenase and tyrosinase. Water, ethanol, and methanol extracts of microalgae were used for the assay. It was found that lipoxygenase and tyrosinase activities were inhibited by the extract of several microalgae. Our results suggest that these species of microalgae have useful antioxidant activity, and they will be further examined for potential biotechnological exploitation. The aim of our screening was to identify potential sources of natural antioxidant compounds, which if found to be sufficiently potent and nontoxic, might eventually replace the chemicals that are currently used as food additives and cosmetics, in order to prevent food spoilage and their oxidation.

    Original languageEnglish
    Pages (from-to)239-247
    Number of pages9
    JournalApplied Biochemistry and Biotechnology
    Volume66
    Issue number3
    DOIs
    StatePublished - 1997

    Bibliographical note

    Funding Information:
    This work was supported by Toyo Suisan Kaisha, Japan and a part of a grant from the Esso Gas Foundation in Japan. The authors thank T. Nishida of the University of Florida for critical reading of the manuscript and helpful suggestions.

    Funding

    This work was supported by Toyo Suisan Kaisha, Japan and a part of a grant from the Esso Gas Foundation in Japan. The authors thank T. Nishida of the University of Florida for critical reading of the manuscript and helpful suggestions.

    FundersFunder number
    Esso Gas Foundation
    Toyo Suisan Kaisha

      Keywords

      • Antioxidant activity
      • Inhibition
      • Lipoxygenase
      • Microalgae
      • Screening
      • Tyrosinase

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