Endothelialization of HA and resorbable HA/TCP bioceramics: Growth and gene regulation

R. E. Unger, L. Kolios, S. Schrödel, K. Peters, C. J. Kirkpatrick

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


The effects of porous hydroxyapatite (HA) and tricalcium phosphate (TCP) on human endothelial cells was investigated. The cells exhibited a normal morphology and pattern of gene expression on these materials. The attachment, spread, growth, and gene regulation on the materials were also analyzed at various time points after addition of cells. Cell growth on the material was visualized by confocal microscopy after staining of cells with Calcein-AM. It was observed that endothelial cells were migrated and formed microvessel-like structures after exposure to angiogenesis-stimilating conditions.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


ConferenceTransactions - 7th World Biomaterials Congress


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