TY - JOUR
T1 - Endemic occurrence of infections by multidrug-resistant Escherichia coli of four unique serotypes in the elderly population of Israel
AU - Wolk, Moshe
AU - Valinsky, Lea
AU - Sompolinsky, David
AU - Sechter, Iancu
AU - Schmidt, Herbert
AU - Tetry, Shaul
AU - Agmon, Vered
PY - 2004/10/15
Y1 - 2004/10/15
N2 - During a period of four years, multidrug-resistant Escherichia coli of particular serotypes have been isolated from 255 elderly (>65 years) patients from four hospitals in central Israel. 83% of the isolates belonged to one of four predominant serotypes (O153:H31, O101:H-, O2:H42, and O102:H6). All isolates were producers of extended spectrum β-lactamases and resistant to ciprofloxacin. To our knowledge, the involved serotypes have hitherto not been reported as etiological agents of extraintestinal human infections (MEDLINE). Pulsed-field gel electrophoresis of isolates from one of the most frequent serotypes indicated a clonal relationship between them. Further investigation of these strains and analysis of their virulence factors may help to confine their spread.
AB - During a period of four years, multidrug-resistant Escherichia coli of particular serotypes have been isolated from 255 elderly (>65 years) patients from four hospitals in central Israel. 83% of the isolates belonged to one of four predominant serotypes (O153:H31, O101:H-, O2:H42, and O102:H6). All isolates were producers of extended spectrum β-lactamases and resistant to ciprofloxacin. To our knowledge, the involved serotypes have hitherto not been reported as etiological agents of extraintestinal human infections (MEDLINE). Pulsed-field gel electrophoresis of isolates from one of the most frequent serotypes indicated a clonal relationship between them. Further investigation of these strains and analysis of their virulence factors may help to confine their spread.
KW - Escherichia coli
KW - Extended spectrum β-lactamase
KW - Geriatric infections
KW - Multidrug resistance
KW - Urinary tract infections
UR - http://www.scopus.com/inward/record.url?scp=5144235102&partnerID=8YFLogxK
U2 - 10.1016/j.femsle.2004.08.042
DO - 10.1016/j.femsle.2004.08.042
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
C2 - 15476973
AN - SCOPUS:5144235102
SN - 0378-1097
VL - 239
SP - 249
EP - 254
JO - FEMS Microbiology Letters
JF - FEMS Microbiology Letters
IS - 2
ER -