Abstract
In this work, we synthesized chiral mesoporous silica (CMS) spheres, which can be used as a potential candidate for chiral separation. The CMS spheres with controllable pore sizes (of 2-3 nm) and high surface areas of ca. 614 m 2 g -1 were synthesized by chiral templating with chiral block copolymers based on poly(ethylene oxide) and dl-glutamic acid [PEO 113-b-(GluA) 10]. The ordered structure of the chiral mesopores was characterized by high-resolution transmission electron microscopy, and the average pore diameters of chiral mesopores were estimated from the nitrogen adsorption-desorption measurements. The enantioselectivity properties and chiral resolution kinetics of the mesopores of silica spheres, after extraction of chiral polymers of PEO 113-b-(l/d-GluA) 10, were scrutinized using a racemic solution of valine and measuring the circular dichroism and optical polarimetery. A chiral selectivity factor of 5.22 was found with a specific enantiomer of valine adsorbed preferably. These results raise the new possibilities of CMS spheres for enantiomeric separation and other enantioselective applications.
Original language | English |
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Pages (from-to) | 1834-1842 |
Number of pages | 9 |
Journal | ACS Applied Materials and Interfaces |
Volume | 1 |
Issue number | 8 |
DOIs | |
State | Published - 26 Aug 2009 |
Keywords
- chiral block copolymers
- chiral mesopores
- enantiomeric separation
- silica spheres