Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial

Anne Laure Sellier-Leclerc; Daniella Magen; Hadas Shasha-Lavsky; Eva Simkova; Arnaud Devresse; Fitsum Guebre-Egziabher; Mini Michael; John C. Lieske; Yaacov Frishberg; Sevcan A. Bakkaloglu; Chebl Mourani; Rola Saqan; Richard Singer; Isabella Guzzo; Nune Makarova; Richard Willey; Cristin Kaspar; John M. Gansner; Jaap W. Groothoff

doi:10.1053/j.ajkd.2025.01.016

Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial

Anne Laure Sellier-Leclerc
, Daniella Magen
, Hadas Shasha-Lavsky
, Eva Simkova
, Arnaud Devresse
, Fitsum Guebre-Egziabher
, Mini Michael
, John C. Lieske
, Yaacov Frishberg
, Sevcan A. Bakkaloglu
, Chebl Mourani
, Rola Saqan
, Richard Singer
, Isabella Guzzo
, Nune Makarova
, Richard Willey
, Cristin Kaspar
, John M. Gansner
, Jaap W. Groothoff

Hospices civils de Lyon
Rambam Health Care Campus Israel
Western Galilee Medical Center of Nahariya
Al Jalila Children's Hospital
Université catholique de Louvain
Hôpital Édouard Herriot
Texas Children's Hospital Houston
Mayo Clinic Rochester, MN
Shaare Zedek Medical Center
Hebrew University of Jerusalem
Gazi University
Hôtel Dieu de France University Hospital
Jordan University of Science and Technology
Canberra Health Services
IRCCS Ospedale pediatrico Bambino Gesù - Roma
Alnylam Pharmaceuticals
University of Amsterdam

Research output: Contribution to journal › Letter › peer-review

8 Scopus citations

Original language	English
Pages (from-to)	285-288
Number of pages	4
Journal	American Journal of Kidney Diseases
Volume	86
Issue number	2
Early online date	13 Mar 2025
DOIs	https://doi.org/10.1053/j.ajkd.2025.01.016
State	Published - Aug 2025
Externally published	Yes

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10.1053/j.ajkd.2025.01.016

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Sellier-Leclerc, A. L., Magen, D., Shasha-Lavsky, H., Simkova, E., Devresse, A., Guebre-Egziabher, F., Michael, M., Lieske, J. C., Frishberg, Y., Bakkaloglu, S. A., Mourani, C., Saqan, R., Singer, R., Guzzo, I., Makarova, N., Willey, R., Kaspar, C., Gansner, J. M., & Groothoff, J. W. (2025). Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial. American Journal of Kidney Diseases, 86(2), 285-288. https://doi.org/10.1053/j.ajkd.2025.01.016

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title = "Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial",

author = "Sellier-Leclerc, \{Anne Laure\} and Daniella Magen and Hadas Shasha-Lavsky and Eva Simkova and Arnaud Devresse and Fitsum Guebre-Egziabher and Mini Michael and Lieske, \{John C.\} and Yaacov Frishberg and Bakkaloglu, \{Sevcan A.\} and Chebl Mourani and Rola Saqan and Richard Singer and Isabella Guzzo and Nune Makarova and Richard Willey and Cristin Kaspar and Gansner, \{John M.\} and Groothoff, \{Jaap W.\}",

year = "2025",

month = aug,

doi = "10.1053/j.ajkd.2025.01.016",

language = "אנגלית",

volume = "86",

pages = "285--288",

journal = "American Journal of Kidney Diseases",

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Sellier-Leclerc, AL, Magen, D, Shasha-Lavsky, H, Simkova, E, Devresse, A, Guebre-Egziabher, F, Michael, M, Lieske, JC, Frishberg, Y, Bakkaloglu, SA, Mourani, C, Saqan, R, Singer, R, Guzzo, I, Makarova, N, Willey, R, Kaspar, C, Gansner, JM & Groothoff, JW 2025, 'Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial', American Journal of Kidney Diseases, vol. 86, no. 2, pp. 285-288. https://doi.org/10.1053/j.ajkd.2025.01.016

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T1 - Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1

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AU - Sellier-Leclerc, Anne Laure

AU - Magen, Daniella

AU - Shasha-Lavsky, Hadas

AU - Simkova, Eva

AU - Devresse, Arnaud

AU - Guebre-Egziabher, Fitsum

AU - Michael, Mini

AU - Lieske, John C.

AU - Frishberg, Yaacov

AU - Bakkaloglu, Sevcan A.

AU - Mourani, Chebl

AU - Saqan, Rola

AU - Singer, Richard

AU - Guzzo, Isabella

AU - Makarova, Nune

AU - Willey, Richard

AU - Kaspar, Cristin

AU - Gansner, John M.

AU - Groothoff, Jaap W.

PY - 2025/8

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UR - https://www.scopus.com/pages/publications/105006933471

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JF - American Journal of Kidney Diseases

IS - 2

ER -

Efficacy and Safety of Lumasiran for Advanced Primary Hyperoxaluria Type 1: 24-Month Follow-up of the Phase 3 ILLUMINATE-C Trial

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