Effects of tetrahydrobiopterin oral treatment in hypoxia-induced pulmonary hypertension in rat

Keyphrases

• Endothelial Nitric Oxide Synthase (eNOS) 100%
• Oral Treatment 100%
• Tetrahydrobiopterin 100%
• Hypoxia-induced Pulmonary Hypertension 100%
• Rat Model 66%
• Pulmonary Hypertension 66%
• Nitric Oxide Production 66%
• Superoxide Production 66%
• Pulmonary Vascular 66%
• Dimerization 33%
• Therapeutic Potential 33%
• Lung 33%
• Hypoxia 33%
• Rescue Therapy 33%
• Oral Administration 33%
• Cyclic GMP 33%
• Nitric Oxide Synthase Activity 33%
• Hypoxia Response 33%
• Pressor Response 33%
• Net Increase 33%
• Right Ventricular Systolic Pressure 33%
• Plateau Phase 33%
• Muscularization 33%
• Right Ventricular Hypertrophy 33%
• Vasorelaxation 33%
• Standard Error of the Mean 33%
• Isolated Perfused Lung 33%
• Pressure Standard 33%
• Pulmonary Vasoconstriction 33%
• Telemetric Monitoring 33%
• Vascular Homeostasis 33%
• Mean Pulmonary Artery Pressure (mPAP) 33%
• Chronic Hypoxia-induced Pulmonary Hypertension 33%
• Placebo Groups 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Endothelial Nitric Oxide Synthase 100%
• Hypoxia-Induced Pulmonary Hypertension 100%
• Tetrahydrobiopterin 100%
• Rat Model 66%
• Superoxide 66%
• Hypoxia 66%
• Nitric Oxide 66%
• Pulmonary Hypertension 66%
• Placebo 33%
• Cyclic GMP 33%
• Hypertensive Factor 33%
• Heart Right Ventricle Hypertrophy 33%