TY - JOUR
T1 - Effective membrane model of the immunological synapse
AU - Raychaudhuri, Subhadip
AU - Chakraborty, Arup K.
AU - Kardar, Mehran
N1 - Funding Information:
Financial support was provided by NIH and NSF.
PY - 2003
Y1 - 2003
N2 - The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T cells and antigen presenting cells during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different stages in the life cycle of T cells. We obtain a minimalist model that captures this experimentally observed phenomenology. A functional renormalization group analysis provides further insights.
AB - The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T cells and antigen presenting cells during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different stages in the life cycle of T cells. We obtain a minimalist model that captures this experimentally observed phenomenology. A functional renormalization group analysis provides further insights.
UR - http://www.scopus.com/inward/record.url?scp=0346216030&partnerID=8YFLogxK
U2 - 10.1103/PhysRevLett.91.208101
DO - 10.1103/PhysRevLett.91.208101
M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???
AN - SCOPUS:0346216030
SN - 0031-9007
VL - 91
JO - Physical Review Letters
JF - Physical Review Letters
IS - 20
ER -