Abstract
The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T cells and antigen presenting cells during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different stages in the life cycle of T cells. We obtain a minimalist model that captures this experimentally observed phenomenology. A functional renormalization group analysis provides further insights.
Original language | English |
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Journal | Physical Review Letters |
Volume | 91 |
Issue number | 20 |
DOIs | |
State | Published - 2003 |
Externally published | Yes |
Bibliographical note
Funding Information:Financial support was provided by NIH and NSF.
Funding
Financial support was provided by NIH and NSF.
Funders | Funder number |
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National Science Foundation | |
National Institutes of Health |