Abstract
Background: The aim of this study was to assess the survival outcomes of head and neck cancer (HNC) by socioeconomic status. Methods: A national retrospective population-based cohort of HNC patients diagnosed in Israel between 2000 and 2017 was conducted. Site of residence and socioeconomic status were correlated with overall survival (OS), controlling for prognostic factors that included tumor site, stage, age, sex, and ethnic group. Results: Overall, 11 826 patients were identified. Patients from high socioeconomic areas had better overall 5-year survival than patients from low socioeconomic areas (p < 0.005). Patients in stage 3 from a high socioeconomic status had a longer median survival rate of 1.5 years than patients in the low-status group. In a cox proportional hazards analysis, we found age >65 (HR 2.91, 95% confidence interval [CI]: 2.75–3.09, p < 0.001) and low socioeconomic group (HR 1.25, 95% CI: 1.18–1.33, p < 0.001) to be correlated with inferior OS. Conclusion: Our findings show that patients with HNC living in low socioeconomic areas had worse OS.
| Original language | English |
|---|---|
| Pages (from-to) | 3001-3009 |
| Number of pages | 9 |
| Journal | Head and Neck |
| Volume | 43 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 2021 |
Bibliographical note
Publisher Copyright:© 2021 Wiley Periodicals LLC.
Funding
The authors wish to thank Mrs. Tobie Kuritsky for editorial assistance, Mrs. Orly Yakir for the statistical analysis, and the people at the Israel national Cancer Registry (INCR) including Dr. Barbara Silverman (director), for collecting, maintaining, and preparing the data for our research.
| Funders | Funder number |
|---|---|
| Israel National Cancer Registry |
Keywords
- head and neck cancer
- rural
- socioeconomic
- survival
