Effect of non-specific interactions on formation and stability of specific complexes

Dino Osmanović, Yitzhak Rabin

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We introduce a simple model to describe the interplay between specific and non-specific interactions. We study the influence of various physical factors on the static and dynamic properties of the specific interactions of our model and show that contrary to intuitive expectations, non-specific interactions can assist in the formation of specific complexes and increase their stability. We then discuss the relevance of these results for biological systems.

Original languageEnglish
Article number205104
JournalJournal of Chemical Physics
Volume144
Issue number20
DOIs
StatePublished - 28 May 2016

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© 2016 Author(s).

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